Too much Ibuprofen linked to male infertility

Ibuprofen male infertility issue joins cardiac risk as painkiller concerns grow

While the testosterone levels in the men taking ibuprofen had not changed, researchers found their pituitary glands were boosting testosterone production anyway, inducing the compensated hypogonadism.

While it is important to note that this was a small study and more research is clearly called for, the fact that ibuprofen is so widely and casually used by so many men makes it a point of concern, particularly for those who intend to start a family.

William Colledge, professor of reproductive physiology at the University of Cambridge, who was not involved in the research, said: "It's a fascinating study that suggests that men should be cautious about using high doses of ibuprofen for extended periods". The men were then divided into two groups, 14 in an ibuprofen group and 17 in a placebo group. Sold under the brand names Advil or Motrin, ibuprofen is a member of the class of drugs known as NSAIDS (nonsteroidal anti-inflammatory drugs).

This is a problem, as the function of LH is to stimulate the production of testosterone, and not to significantly surpass testosterone levels. As this happened, the ratio of testosterone to luteinizing hormones decreased.

This study might be especially troubling for athletes; Bernard Jégou, one of the study's co-authors, told CNN that many athletes take ibuprofen regularly to combat the aches and pains that accompany their sport, and warns that long-term usage like this could do irreversible damage.

Ice, freezing rain possible Sunday
Freezing rain, possibly mixed with sleet is possible between 3 and 4 a.m. and then freezing rain likely after 4 a.m. Temperatures will warm faster from the south, so there will be a quicker transition from anything frozen to rain.

The findings are certainly significant, as the 1,200mg of ibuprofen given to the participants each day is far below the suggested daily maximum of 3,200mg per day.

The researchers also pointed out the risk of those with compensated hypogonadism progressing to overt primary hypogonadism, which is characterized by "low circulating testosterone and prevalent symptoms including reduced libido, reduced muscle mass and strength, and depressed mood and fatigue".

So researchers wanted to look into what happened in adult males who took ibuprofen, which had the strongest results in the earlier study.

The hormonal imbalance caused compensated hypogonadism, which is a condition linked to decreased male fertility, depression, and an increased risk of heart attack or stroke.

Related News:

  • USA  issues new sanctions on Iran over missiles

    USA issues new sanctions on Iran over missiles

    At Friday rallies in Iran, pro-government demonstrators chanted "Death to America" and "Death to Israel". The Security Council "rebuffed the U.S.' naked attempt to hijack its mandate", Mr.
    Packers promote Brian Gutekunst as new general manager

    Packers promote Brian Gutekunst as new general manager

    Schneider, a Wisconsin native, was the director of football operations for the Packers before being hired by the Seahawks in 2010. Green Bay submitted paperwork for permission to interview #Seahawks Super Bowl-winning GM John Schneider, I'm told.
    PEI unemployment rate hits 40-year low

    PEI unemployment rate hits 40-year low

    The jobless rate in Windsor fell to 6.1 per cent from 6.3 per cent, with an increase in employment and labour force. In Regina, job numbers dropped 0.1 of a percentage point to 4.7, while Saskatoon held steady at 7.6 per cent.
  • H&M slammed over advert of black child in 'monkey' hoodie

    H&M slammed over advert of black child in 'monkey' hoodie

    Therefore, we have not only removed the image from our channels, but also the garment from our product offering globally. H&M, based in Sweden, issued an apology via the New York Daily News on Monday from its Stockholm headquarters.
    'Jeopardy' host Trebek undergoes surgery

    'Jeopardy' host Trebek undergoes surgery

    " Jeopardy! " host Alex Trebek is recovering after undergoing brain surgery and has taken a medical leave from hosting duties. The rest of the broadcast schedule will remain uninterrupted, the statement said.
    Malware Mimics Uber Android App to Steal Passwords

    Malware Mimics Uber Android App to Steal Passwords

    When the user goes to login with the information, it is sent to a remote server controlled by the attackers. The malware tries to pass itself as the original Uber app but it is not available in the Google Play Store.
  • Gregg Popovich says Spurs star suffered tear in shoulder

    Gregg Popovich says Spurs star suffered tear in shoulder

    He'll miss a few more after suffering a partial tear in his left shoulder during Friday's 103-89 win over Suns. Despite numerous injuries, the Spurs are 27-14 and now in third place in the Western Conference standings.
    Trump moves back his 'Fake News Awards,' citing high interest

    Trump moves back his 'Fake News Awards,' citing high interest

    In November, he tweeted about a competition among news networks for the "Fake News Trophy", excluding Fox News. Subjects will cover Dishonesty & Bad Reporting in various categories from the Fake News Media.
    Celebs Are Bringing Activists As Their Dates To Today's Golden Globes

    Celebs Are Bringing Activists As Their Dates To Today's Golden Globes

    Woodley is set to bring Calina Lawrence , a Suquamish Tribe member and activist for Native American treaty and water rights.
  • Razer's Project Linda Turns Your Razer Phone into a Laptop PC

    Razer's Project Linda Turns Your Razer Phone into a Laptop PC

    The infamous gaming company is known for their wide variety of gaming peripherals including laptops, mice, displays, and more. Other than that, it also carries 3.5mm audio jack, USB-A port, USB-C charging port, 720p webcam, and dual-array microphone.
    Smoke billows from Trump Tower in NYC as fire injures 2

    Smoke billows from Trump Tower in NYC as fire injures 2

    The twitter account of Boston 25 News released images of these firefighters on the roof of Trump Tower . I've been sent out of college, with honors and such, on the search for the American Dream.
    SpaceX's Zuma mission may finally be ready to zoom into space

    SpaceX's Zuma mission may finally be ready to zoom into space

    SpaceX now can look forward to its next major test for the year - launching its huge heavy-duty rocket for the first time ever. Aerospace and defense company Northrop Grumman was responsible for securing SpaceX's launch services for the Zuma mission.


Most liked

Weather Outlook: Snowfall possible Friday night
THURSDAY: The warming trend continues for Thursday, with a high temperature of 64 degrees, and the chance for a few rain showers. Wind gusts in these areas could reach as high as 30 miles per hour , causing patchy blowing and drifting snow.

Jennifer Lawrence is a Russian spy in Red Sparrow trailer
This film will be telling the story of fictional character Dominika Egorova as she is tricked into becoming a Sparrow recruit. Dominika goes through a sadistic training process and turns out to be the most unsafe Sparrow in the history of the program.

CTE Expert Calls BS on Cam Newton's Claim of an Eye Injury
If the concussion protocol was not properly followed the team is subject to discipline, including a $150,000 fine. When a reported noted that Jordan's sauce comment was a callback to Newton's joke, Jordan said, "Petty, right?"

Rivals.com reporter Courtney Roland missing in Houston
They discovered her cellphone and different assets inside, cops stated, while her satchel was found at a close-by business. They said that she appeared "unharmed" in an updated Tweet and said that she would be taken to a hospital for evaluation.

CES 2018: Samsung reveals enormous modular MicroLED television you can build yourself
Below you can see a close up of a conventional LED display panel segment (left), compared to a MicroLED segment (right). This further hints at Samsung's visionary efforts in consumer offerings presented via the modular MicroLED TV.

Two injured in Stockholm metro blast
Police cordoned off the station and the square where the blast happened as the bomb squad moved in to investigate. Numerous illegal hand grenades found in Sweden are being imported from former Yugoslav nations, he said.

Jaguars' defense shuts down Bills in AFC wild-card game
The Bills' Cinderella story continues into the playoffs with an AFC wild-card matchup with the Jaguars in Jacksonville. Quarterback Tyrod Taylor left the game after being thrown to the ground by Dante Fowler Jr. and hitting his head hard.

Arsenal manager Wenger gets three-match ban
Arsenal have named their side and substitutes to tackle Nottingham Forest in an FA Cup tie at the City Ground this afternoon. The Gunners have won three of the last four FA Cups, including last year's 2-1 upset of Chelsea in the final.

Panthers look to continue wild card weekend success
Newton's 56-yard touchdown pass to Christian McCaffrey cut the Saints lead to 31-26 with just over four minutes to play. If you have any questions or comments, make them during the program and we will try to use them.

Two area Kmart stores are closing in early April
In its most recent quarter, Sears Holdings said comparable sales fell 17 percent at its namesake stores and 13 percent at Kmart. After careful consideration, Macy's has made a decision to close the Novato Furniture store in mid to late March of 2018.

Fodder scam: Lalu Prasad Yadav gets 3.5 years in jail
Lalu's son and RJD leader Tej Pratap said the former would get bail soon, adding the "feudal power" could not break them. His son Tejashwi Yadav said that they will approach the high court and also apply for bail after studying the sentence.

ESPN's Katie Nolan calls Donald Trump a 'stupid person' - WARNING GRAPHIC LANGUAGE
Since then she's appeared on a variety of TV shows, including Hill's "The Six" and Dan Le Batard's "Highly Questionable". Nolan was likely spared suspension because her comment was made on a talk show, not via social media.

Success! Trump's Bogus Election Integrity Commission Is Over
Clinton received more than 2.8 million more votes than Trump nationwide. Jon Husted has said voter fraud does exist in OH , but it's rare.

Falcons lead Rams 13-10 at halftime of NFC wild-card game
And at the head of L.A.'s scoring monster are a pair of 23-year-olds who have emerged as two of the best at their positions. Last year, it was Atlanta who had the all-conquering offence - what a difference a 12 months makes in the NFL.

McDonough bids farewell to Gruden during broadcast
The Raiders extended Derek Carr's contract last summer, paying the two-time Pro Bowl quarterback $125 million over five seasons. Gibbs returned to coaching in 2004 and his second stint in Washington wasn't almost as effective as his first.